What is Serotonin Syndrome?

What causes it? Too much intake of serotonin

What are the sources of serotonin?

-SSRIs (e.g. Celexa, Lexapro, Prozac, Luvox, Paxil, Zoloft, Viibryd, Brintellix)

-SNRIs (e.g. Cymbalta, Effexor, Pristiq, Fetzima)

-TCAs (e.g. Norpramin, Pamelor, Elavil, Anafranil, Silenor, etc.)

-Triptans (e.g. medications that end with -triptan)






-St. John’s Wort

What are the symptoms? 

-Changes in mental state (hallucinations, unresponsiveness, etc.)

-Muscle problems (muscle twitching, muscle tightness, or coordination problems)

-Feel your heart racing

-Sweating or fever

-Nausea, vomiting, or diarrhea

What should I do?

Call 911 or go to the closest emergency room immediately.


By Dr. Terra Caudill, MD, MS